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| Week 8 - Thursday, Oct. 16, 2008 | ||
| Florida State Seminoles at North Carolina State Wolfpack | ||
 Florida State 29 |  North Carolina State 20 | |
| Brigham Young Cougars at TCU Horned Frogs | ||
 Brigham Young 24 |  TCU 22 | |
| Week 8 - Friday, Oct. 17, 2008 | ||
| Hawaii Warriors at Boise State Broncos | ||
 Boise State 42 |  Hawaii 14 | |
| Week 8 - Saturday, Oct. 18, 2008 | ||
| Texas Tech Red Raiders at Texas A&M Aggies | ||
 Texas Tech 46 |  Texas A&M 21 | |
| Purdue Boilermakers at Northwestern Wildcats | ||
 Northwestern 23 |  Purdue 22 | |
| Wisconsin Badgers at Iowa Hawkeyes | ||
 Iowa 27 |  Wisconsin 19 | |
| Syracuse Orange at South Florida Bulls | ||
 South Florida 43 |  Syracuse 14 | |
| Connecticut Huskies at Rutgers Scarlet Knights | ||
 Rutgers 28 |  Connecticut 25 | |
| Wake Forest Demon Deacons at Maryland Terrapins | ||
 Maryland 22 |  Wake Forest 18 | |
| Memphis Tigers at East Carolina Pirates | ||
 East Carolina 33 |  Memphis 28 | |
| Georgia Tech Yellow Jackets at Clemson Tigers | ||
 Clemson 23 |  Georgia Tech 21 | |
| Western Michigan Broncos at Central Michigan Chippewas | ||
 Central Michigan 34 |  Western Michigan 26 | |
| Miami (Ohio) RedHawks at Bowling Green Falcons | ||
 Bowling Green 30 |  Miami (Ohio) 22 | |
| Nebraska Cornhuskers at Iowa State Cyclones | ||
 Nebraska 34 |  Iowa State 23 | |
| Vanderbilt Commodores at Georgia Bulldogs | ||
 Georgia 31 |  Vanderbilt 13 | |
| Akron Zips at Eastern Michigan Eagles | ||
 Eastern Michigan 28 |  Akron 25 | |
| Colorado State Rams at Utah Utes | ||
 Utah 36 |  Colorado State 18 | |
| Southern Mississippi Golden Eagles at Rice Owls | ||
 Rice 35 |  Southern Mississippi 31 | |
| Baylor Bears at Oklahoma State Cowboys | ||
 Oklahoma State 46 |  Baylor 25 | |
| Pittsburgh Panthers at Navy Midshipmen | ||
 Pittsburgh 30 |  Navy 28 | |
| Southern California Trojans at Washington State Cougars | ||
 Southern California 48 |  Washington State 9 | |
| Kansas Jayhawks at Oklahoma Sooners | ||
 Oklahoma 43 |  Kansas 20 | |
| Mississippi Rebels at Alabama Crimson Tide | ||
 Alabama 38 |  Mississippi 20 | |
| North Carolina Tar Heels at Virginia Cavaliers | ||
 North Carolina 24 |  Virginia 17 | |
| Ohio State Buckeyes at Michigan State Spartans | ||
 Ohio State 26 |  Michigan State 21 | |
| Middle Tennessee Blue Raiders at Louisville Cardinals | ||
 Louisville 35 |  Middle Tennessee 19 | |
| Miami (Fla.) Hurricanes at Duke Blue Devils | ||
 Miami (Fla.) 23 |  Duke 18 | |
| Army Black Knights at Buffalo Bulls | ||
 Buffalo 30 |  Army 15 | |
| Stanford Cardinal at UCLA Bruins | ||
 UCLA 25 |  Stanford 21 | |
| Marshall Thundering Herd at UAB Blazers | ||
 UAB 26 |  Marshall 24 | |
| Toledo Rockets at Northern Illinois Huskies | ||
 Northern Illinois 28 |  Toledo 24 | |
| Utah State Aggies at Nevada Wolf Pack | ||
 Nevada 42 |  Utah State 20 | |
| Michigan Wolverines at Penn State Nittany Lions | ||
 Penn State 40 |  Michigan 13 | |
| San Diego State Aztecs at New Mexico Lobos | ||
 New Mexico 30 |  San Diego State 19 | |
| Oregon State Beavers at Washington Huskies | ||
 Oregon State 37 |  Washington 20 | |
| Kansas State Wildcats at Colorado Buffaloes | ||
 Kansas State 32 |  Colorado 29 | |
| Florida Atlantic Owls at Western Kentucky Hilltoppers | ||
 Western Kentucky 25 |  Florida Atlantic 24 | |
| Florida International Golden Panthers at Troy Trojans | ||
 Troy 31 |  Florida International 22 | |
| North Texas Mean Green at Louisiana-Monroe Warhawks | ||
 Louisiana-Monroe 39 |  North Texas 25 | |
| Arkansas State Red Wolves at La.-Lafayette Ragin Cajuns | ||
 La.-Lafayette 37 |  Arkansas State 35 | |
| Idaho Vandals at Louisiana Tech Bulldogs | ||
 Louisiana Tech 39 |  Idaho 23 | |
| Mississippi State Bulldogs at Tennessee Volunteers | ||
 Tennessee 24 |  Mississippi State 13 | |
| Arkansas Razorbacks at Kentucky Wildcats | ||
 Kentucky 29 |  Arkansas 15 | |
| San Jose State Spartans at New Mexico State Aggies | ||
 San Jose State 30 |  New Mexico State 25 | |
| Texas-El Paso Miners at Tulsa Golden Hurricane | ||
 Tulsa 46 |  Texas-El Paso 25 | |
| Missouri Tigers at Texas Longhorns | ||
 Texas 38 |  Missouri 36 | |
| Houston Cougars at Southern Methodist Mustangs | ||
 Houston 46 |  Southern Methodist 30 | |
| Indiana Hoosiers at Illinois Fighting Illini | ||
 Illinois 37 |  Indiana 24 | |
| LSU Tigers at South Carolina Gamecocks | ||
 LSU 31 |  South Carolina 22 | |
| Virginia Tech Hokies at Boston College Eagles | ||
 Virginia Tech 23 |  Boston College 22 | |
| Air Force Falcons at UNLV Rebels | ||
 Air Force 26 |  UNLV 23 | |
| California Golden Bears at Arizona Wildcats | ||
 California 27 |  Arizona 24 | |