The Giants' run of promising play ended last week in a dispiriting shutout loss at home. That game ended their season. Odell Beckham likely will miss another game, and No. 3 wideout Russell Shepard (ankle) also could sit out. The Colts have everything to play for, and they have the defense to contain Saquon Barkley. Lay it.

The Colts defense has been phenomenal the last three weeks. It shutout the Cowboys last week, and has allowed only 9 points per game the last three. Now it faces a Giants offense that looks like it will be without Odell Beckham yet again. Still, the spread is a little too large for me to feel comfortable with, but I feel this total is too high and provides some value.