Simulation Picks
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Understanding Public and Money
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Expert Picks
I expect Carolina to bounce back this season, but they're having to travel cross country for Week 1 and Cam Newton got next to no work in the preseason. He could come out a little rusty, and that might spell trouble against what should be an improved 49ers defense. Kyle Shanahan knows this opponent well and should have a few things up his sleeve on offense. The 49ers, who have dominated in recent Week 1 matchups, shock us again this week by hanging with the Panthers and possibly pulling out a win.