The Jaguars were the trendy pick to be the proverbial breakout team in the NFL this season, but instead they look headed toward a familiar area of futility. They self-destructed in last week’s 19-17 loss to the Ravens after forcing three fourth-quarter turnovers. Meanwhile, the Colts, despite their issues with defense and protection, are a much better team than they’ve shown thus far. I think last week’s last-minute 26-22 win over the Chargers is going to send them toward a winning streak, and they will beat up the AFC South rival Jaguars again on Sunday.

This is the first of three games across the pond this year. The Colts put on a good showing last week in a victory over San Diego, while the Jags are coming off a sloppy home loss to the Ravens. The Jags hope Blake Bortles can shake his early-season interception funk and bounce back against a secondary that gives up over 305 passing yards per game. I think you’ll see the Jags look better offensively, but it won't be enough. Indy wins and covers.