The 49ers' defenses matches up well versus the Seahawks, who are coming into this game limping offensively. What helps Seattle is its defense is still intact and facing a unit quarterbacked by Blaine Gabbert. I look for a dominating defensive performance by Seattle as the Seahawks cover.

I think this is a proverbial "get-well" game for the Seahawks, and look for them to continue their dominance of the 49ers. Seattle is 8-0-1 ATS in the last nine meetings. Similar to last season, San Francisco's Week 1 performance will prove to be an aberration versus its baseline potential, and last week's performance against the Panthers is a more accurate gauge of its potential. The Seahawks have scored just 13 points in three games, but I think they'll break through against a 49ers defense that yielded 529 yards to Carolina.

I get it. The Seahawks have been one of the best teams in the league for years and the 49ers have been atrocious. But the 49ers have now scored 28 points on a good Rams D and 27 points on a good Panthers D. They shut down a limited offense in Week 1, and get to face a limited offense again in Week 3. Put this matchup in December with a healthier Seahawks offense and I like Seattle. In these conditions, the perpetually slow-starting Seahawks and their pedestrian offense let the 49ers stay close through four quarters.