| Date | Player | Pos. | Transaction |
| 5/12 | Edgar Gonzalez | 2B | Purchased From Minors |
| 5/12 | Callix Crabbe | 2B | Designated for Assignment |
| 5/11 | Bryan Corey | P | Traded From, Boston (for future considerations) |
| 5/11 | Joe Thatcher | P | Sent to Minors |
| 5/11 | Bryan Corey | P | Purchased From Minors |
| 5/10 | Glendon Rusch | P | Outrighted to Minors |
| 5/9 | Luke Carlin | C | Purchased From Minors |
| 5/9 | Jim Edmonds | CF | Released |
| 5/9 | Jody Gerut | RF | Called Up from Minors |
| 5/9 | Sean Henn | P | Acquired Off Waivers From, NY Yankees |
| 5/9 | Colt Morton | C | Sent to Minors |
| 5/8 | Shawn Estes | P | Purchased From Minors |
| 5/8 | Kevin Cameron | P | Placed on 15-Day DL, (Right elbow sprain) |
| 4/29 | Mauro Zarate | P | Outrighted to Minors |
| 4/29 | Mauro Zarate | P | Called Up from Minors, - Not to Report |
| 4/23 | Josh Banks | P | Sent to Minors |
| 4/23 | Josh Banks | P | Acquired Off Waivers From, Toronto |
| 4/22 | Clay Hensley | P | Sent to Minors, For Rehabilitation |
| 4/15 | Enrique Gonzalez | P | Outrighted to Minors |
| 4/15 | Kevin Cameron | P | Called Up from Minors |
| 4/8 | Michael Barrett | C | Placed on 15-Day DL, (Right elbow strain) |
| 4/8 | Colt Morton | C | Called Up from Minors |
| 4/5 | Jody Gerut | RF | Sent to Minors |
| 4/5 | Jim Edmonds | CF | Recalled From Minors, Rehab Assignment |
| 4/5 | Jim Edmonds | CF | Removed From 15-Day DL, (Right calf strain - out 2-4 weeks) |
| 4/3 | Jim Edmonds | CF | Sent to Minors, For Rehabilitation |
| 3/26 | Glendon Rusch | P | Purchased From Minors |
| 3/26 | Tim Stauffer | P | Placed on 60-Day DL, (Right shoulder strain) |
| 3/26 | Mark Prior | P | Placed on 60-Day DL, (Right shoulder strain) |
| 3/26 | Justin Huber | 1B | Traded From, Kansas City (for future considerations) |
| 3/26 | Clay Hensley | P | Placed on 15-Day DL, (Right shoulder strain) |
| 3/26 | Justin Hampson | P | Placed on 15-Day DL, (Tendinitis, left shoulder) |
| 3/26 | Carlos Guevara | P | Placed on 15-Day DL, (Strained right groin) |
| 3/26 | Luis Rodriguez | 3B | Sent to Minors |
| 3/26 | Kevin Cameron | P | Sent to Minors |
| 3/26 | Jody Gerut | RF | Purchased From Minors |
| 3/25 | Craig Stansberry | 2B | Sent to Minors |
| 3/25 | Oscar Robles | 2B | Sent to Minors |
| 3/25 | Brian Myrow | 1B | Sent to Minors |
| 3/23 | Chase Headley | 3B | Sent to Minors |
| 3/22 | Robert Fick | 1B | Released |
| 3/22 | Jeff DaVanon | CF | Released |
| 3/18 | Mauro Zarate | P | Sent to Minors |
| 3/18 | Colt Morton | C | Sent to Minors |
| 2/19 | Drew Macias | RF | Outrighted to Minors |
| 2/14 | Drew Macias | RF | Designated for Assignment |
| 2/14 | Josh Bard | C | Signed, ( 2008)(avoids arbitration) |
| 2/14 | Tony Clark | 1B | Signed as Free Agent, ( 2008) |
| 2/10 | Tony Clark | 1B | Signed as Free Agent, ( 2008) |
| 2/5 | Enrique Gonzalez | P | Acquired Off Waivers From, Washington |
| 2/4 | Khalil Greene | SS | Signed, ( 2008-2009)(two-year extension, avoids arbitration) |
| 1/21 | Jody Gerut | RF | Signed to a Minor League Contract |
| 1/18 | Wilfredo Ledezma | P | Signed, ( 2008)(avoids arbitration) |
| 12/26 | Mark Prior | P | Signed as Free Agent, ( 2008) |
| 12/21 | Robert Fick | 1B | Signed to a Minor League Contract |
| 12/21 | Jeff DaVanon | CF | Signed to a Minor League Contract |
| 12/19 | Michael Barrett | C | Signed, ( 2008)(avoids arbitration) |
| 12/18 | Tadahito Iguchi | 2B | Signed as Free Agent, ( 2008) |
| 12/15 | Jim Edmonds | CF | Traded From, St. Louis (with cash for 3B David Freese) |
| 12/14 | Shawn Estes | P | Signed to a Minor League Contract |
| 12/14 | Glendon Rusch | P | Signed to a Minor League Contract |
| 12/12 | Jason Lane | CF | Not Offered Contract and Became Free Agent, (non-tendered) |
| 12/12 | Ryan Ketchner | P | Not Offered Contract and Became Free Agent, (non-tendered) |
| 12/12 | Tadahito Iguchi | 2B | Signed as Free Agent, ( 2008) |
| 12/12 | Jack Cassel | P | Not Offered Contract and Became Free Agent, (non-tendered) |
| 12/12 | Morgan Ensberg | 3B | Not Offered Contract and Became Free Agent, (non-tendered) |
| 12/10 | Randy Wolf | P | Signed as Free Agent, ( 2008) |
| 12/7 | Michael Barrett | C | Accepted Arbitration - added to roster |
| 12/3 | Hiram Bocachica | RF | Signed to Play in Japan, (Seibu Lions) |
| 12/1 | Randy Wolf | P | Signed as Free Agent, ( 2008) |
| 11/29 | Terrmel Sledge | LF | Released |
| 11/29 | Terrmel Sledge | LF | Signed to Play in Japan, (Nippon Ham Fighters) |
| 11/20 | Marshall McDougall | 3B | Signed to a Minor League Contract |
| 11/19 | Greg Maddux | P | Signed, ( 2008)(restructured one-year contract) |
| More Transactions |
| Posted Tue May 13 14:44:45 EDT 2008 |
