| Date | Player | Pos. | Transaction |
| 5/11 | Chris Denorfia | CF | Placed on 15-Day DL, (Lower back tightness) |
| 5/11 | Rich Harden | P | Recalled From Minors, Rehab Assignment |
| 5/11 | Rich Harden | P | Removed From 15-Day DL, (Right shoulder strain) |
| 5/10 | Travis Buck | RF | Removed From 15-Day DL, (Shin splints) |
| 5/10 | Travis Buck | RF | Sent to Minors |
| 5/10 | Kiko Calero | P | Sent to Minors, For Rehabilitation |
| 5/9 | Keith Foulke | P | Removed From 15-Day DL, (Neck stiffness) |
| 5/9 | Keith Foulke | P | Recalled From Minors, Rehab Assignment |
| 5/8 | Dallas Braden | P | Sent to Minors |
| 5/5 | Keith Foulke | P | Sent to Minors, For Rehabilitation |
| 5/3 | Travis Buck | RF | Sent to Minors, For Rehabilitation |
| 5/1 | Rich Harden | P | Sent to Minors, For Rehabilitation |
| 4/26 | Lenny DiNardo | P | Sent to Minors |
| 4/26 | Justin Duchscherer | P | Removed From 15-Day DL, (Strained right biceps) |
| 4/25 | Kirk Saarloos | P | Outrighted to Minors |
| 4/24 | Travis Buck | RF | Placed on 15-Day DL, (Shin splints) |
| 4/24 | Frank Thomas | DH | Signed as Free Agent, ( 2008) |
| 4/24 | Eric Chavez | 3B | Transferred to 60-Day DL, (Recurring back pain) |
| 4/23 | Kirk Saarloos | P | Designated for Assignment |
| 4/23 | Rajai Davis | CF | Acquired Off Waivers From, San Francisco |
| 4/22 | Dallas Braden | P | Called Up from Minors |
| 4/21 | Justin Duchscherer | P | Sent to Minors, For Rehabilitation |
| 4/20 | Keith Foulke | P | Placed on 15-Day DL, (Neck stiffness) |
| 4/16 | Fernando Hernandez | P | Drafted Player Returned to Minors |
| 4/14 | Fernando Hernandez | P | Designated for Assignment |
| 4/14 | Kirk Saarloos | P | Purchased From Minors |
| 4/10 | Rich Harden | P | Placed on 15-Day DL, (Right shoulder strain) |
| 4/10 | Joey Devine | P | Called Up from Minors |
| 4/9 | Dan Johnson | 1B | Designated for Assignment |
| 4/9 | Greg Smith | P | Purchased From Minors |
| 4/8 | Justin Duchscherer | P | Placed on 15-Day DL, (Strained right biceps) |
| 4/8 | Chad Gaudin | P | Removed From 15-Day DL, (Minor hip surgery) |
| 3/29 | Dallas Braden | P | Sent to Minors |
| 3/24 | Eric Chavez | 3B | Placed on 15-Day DL, (Recurring back pain) |
| 3/24 | Kiko Calero | P | Placed on 60-Day DL, (Torn right rotator cuff) |
| 3/24 | Chad Gaudin | P | Placed on 15-Day DL, (Minor hip surgery) |
| 3/24 | Mike Sweeney | DH | Purchased From Minors |
| 3/18 | Joey Devine | P | Sent to Minors |
| 3/16 | Jerry Blevins | P | Sent to Minors |
| 3/16 | Matthew LeCroy | 1B | Released |
| 3/9 | Kevin Melillo | 2B | Sent to Minors |
| 3/9 | Dan Meyer | P | Sent to Minors |
| 2/15 | Matthew LeCroy | 1B | Signed to a Minor League Contract |
| 2/15 | Jeremy Brown | C | Retired |
| 2/10 | Mike Sweeney | DH | Signed to a Minor League Contract |
| 2/8 | Keith Foulke | P | Signed as Free Agent, ( 2008) |
| 1/25 | Jeff Fiorentino | CF | Acquired Off Waivers From, Cincinnati |
| 1/25 | Chad Gaudin | P | Signed, ( 2008)(avoids arbitration) |
| 1/25 | Ruddy Lugo | P | Designated for Assignment |
| 1/18 | Joe Blanton | P | Signed, ( 2008)(avoids arbitration) |
| 1/17 | Huston Street | P | Signed, ( 2008)(avoids arbitration) |
| 1/15 | Kirk Saarloos | P | Signed to a Minor League Contract |
| 1/14 | Joey Devine | P | Traded From, Atlanta (w/RHP Jamie Richmond for OF Mark Kotsay) |
| 1/13 | Joey Devine | P | Traded From, Atlanta (for CF Mark Kotsay) |
| 1/11 | Emil Brown | LF | Signed as Free Agent, ( 2008) |
| 1/11 | Danny Putnam | CF | Designated for Assignment |
| 1/9 | Justin Duchscherer | P | Signed, ( 2008)(avoids arbitration) |
| 1/3 | Ryan Sweeney | LF | Traded From, Chi. White Sox (for OF Nick Swisher, four-player deal) |
| 12/14 | Dana Eveland | P | Traded From, Arizona (for RHP Dan Haren in eight-player deal) |
| 12/13 | Kiko Calero | P | Signed as Free Agent, ( 2008) |
| 12/12 | Jose Garcia | P | Not Offered Contract and Became Free Agent, (non-tendered) |
| 12/12 | Lenny DiNardo | P | Signed, ( 2008)(avoids arbitration) |
| 12/12 | Kiko Calero | P | Not Offered Contract and Became Free Agent, (non-tendered) |
| 12/6 | Jose Garcia | P | Designated for Assignment |
| 12/6 | Jay Marshall | P | Acquired Off Waivers From, Boston |
| 11/21 | Troy Cate | P | Signed to a Minor League Contract |
| 11/21 | Chris Gissell | P | Signed to a Minor League Contract |
| 11/21 | Justin Knoedler | C | Signed to a Minor League Contract |
| 11/21 | Todd Linden | LF | Signed to a Minor League Contract |
| More Transactions |
| Posted Tue May 13 14:44:44 EDT 2008 |
