| Date | Player | Pos. | Transaction |
| 7/21 | Andrew Sisco | P | Transferred to 60-Day DL, (Left elbow surgery - out for season) |
| 7/20 | Adam Russell | P | Sent to Minors |
| 7/20 | D.J. Carrasco | P | Called Up from Minors |
| 7/20 | Jose Contreras | P | Placed on 15-Day DL, (Right elbow tendinitis) |
| 7/18 | Bobby Jenks | P | Removed From 15-Day DL, (Left scapula bursitis) |
| 7/18 | Bobby Jenks | P | Recalled From Minors, Rehab Assignment |
| 7/17 | D.J. Carrasco | P | Sent to Minors |
| 7/17 | Esteban Loaiza | P | Sent to Minors, For Rehabilitation |
| 7/16 | Pablo Ozuna | 3B | Refused Minor League Assignment - Free Agent |
| 7/14 | Bobby Jenks | P | Sent to Minors, For Rehabilitation |
| 7/9 | Bobby Jenks | P | Placed on 15-Day DL, (Left scapula bursitis) |
| 7/9 | D.J. Carrasco | P | Purchased From Minors |
| 7/8 | Pablo Ozuna | 3B | Designated for Assignment |
| 7/8 | Paul Konerko | 1B | Removed From 15-Day DL, (Left oblique strain) |
| 7/8 | Paul Konerko | 1B | Recalled From Minors, Rehab Assignment |
| 7/4 | Esteban Loaiza | P | Recalled From Minors, Rehab Assignment |
| 7/4 | Paul Konerko | 1B | Sent to Minors, For Rehabilitation |
| 6/17 | Dewayne Wise | CF | Purchased From Minors |
| 6/17 | Paul Konerko | 1B | Placed on 15-Day DL, (Left oblique strain) |
| 6/16 | Esteban Loaiza | P | Sent to Minors, For Rehabilitation |
| 6/13 | Esteban Loaiza | P | Placed on 15-Day DL, (Right shoulder inflammation) |
| 6/4 | Dewayne Wise | CF | Outrighted to Minors |
| 6/4 | Esteban Loaiza | P | Signed as Free Agent, ( 2008) |
| 6/4 | Ehren Wassermann | P | Sent to Minors |
| 5/31 | Dewayne Wise | CF | Designated for Assignment |
| 5/31 | Juan Uribe | 2B | Removed From 15-Day DL, (Strained left hamstring) |
| 5/31 | Juan Uribe | 2B | Recalled From Minors, Rehab Assignment |
| 5/29 | Danny Richar | 2B | Recalled From Minors, Rehab Assignment |
| 5/29 | Danny Richar | 2B | Removed From 15-Day DL, (Stress fracture in rib cage) |
| 5/29 | Danny Richar | 2B | Sent to Minors |
| 5/27 | Juan Uribe | 2B | Sent to Minors, For Rehabilitation |
| 5/23 | Danny Richar | 2B | Sent to Minors, For Rehabilitation |
| 5/23 | Juan Uribe | 2B | Placed on 15-Day DL, (Strained left hamstring) |
| 5/23 | Dewayne Wise | CF | Purchased From Minors |
| 5/9 | Ray King | P | Signed to a Minor League Contract |
| 5/9 | Ryan O'Malley | P | Signed to a Minor League Contract |
| 5/7 | Gookie Dawkins | 2B | Signed to a Minor League Contract |
| 5/6 | Alexei Ramirez | CF | Reinstated From Restricted List |
| 5/2 | Alexei Ramirez | CF | Placed on Restricted List, (visa issues preventing trip to Canada) |
| 4/27 | Ehren Wassermann | P | Called Up from Minors |
| 4/26 | Mike MacDougal | P | Sent to Minors |
| 4/18 | Jerry Owens | CF | Sent to Minors |
| 4/18 | Jerry Owens | CF | Recalled From Minors, Rehab Assignment |
| 4/18 | Jerry Owens | CF | Removed From 15-Day DL, (Right adductor tear) |
| 4/16 | Jim Thome | DH | Reinstated From League Suspension |
| 4/15 | Jim Thome | DH | Starting to Serve Suspension |
| 4/15 | Jim Thome | DH | Suspension Announced By League, (one game) |
| 4/12 | Jerry Owens | CF | Sent to Minors, For Rehabilitation |
| 4/4 | Jeff DaVanon | CF | Signed to a Minor League Contract |
| 3/30 | Danny Richar | 2B | Placed on 15-Day DL, (Stress fracture in rib cage) |
| 3/30 | Jerry Owens | CF | Placed on 15-Day DL, (Right adductor tear) |
| 3/30 | Ehren Wassermann | P | Sent to Minors |
| 3/25 | Josh Fields | 3B | Sent to Minors |
| 3/19 | Andrew Sisco | P | Sent to Minors |
| 3/19 | Donny Lucy | C | Sent to Minors |
| 3/12 | Lance Broadway | P | Sent to Minors |
| 3/12 | Dewon Day | P | Sent to Minors |
| 3/12 | Charlie Haeger | P | Sent to Minors |
| 2/21 | Tomo Ohka | P | Signed to a Minor League Contract |
| More Transactions |
| Posted Wed Jul 23 22:32:47 EDT 2008 |
