While Charlie Weis is no pushover, I believe that Mark Mangino could school him thoroughly.
Weis looks like he probably snacks on a few buckets of chicken preparing for a game (and don't forget to wash it down with the gravy either). Whereas Mangino looks as if he snacks on a few small children. Both are amazing feats, but I'd definitely have to put money down on Mangino if it came down to it.
I'm gonna go with Weis only because I believe he is more physically "fit" for the job. For Mangino, I think one of those dogs might get stuck in his extra chin and he'd end up needing the Medics to fish it out!