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| WEEK 6 | | Tuesday, Oct. 2 |
| Matchup | TV | Time/Result | | Marshall @ Memphis | ESPN2 | MEM 24, MRSHL 21 | | Wednesday, Oct. 3 |
| Matchup | TV | Time/Result | | Rice @ Southern Mississippi | | RICE 31, USM 29 | | Thursday, Oct. 4 |
| Matchup | TV | Time/Result | | Tennessee-Martin @ Jacksonville State | | JAXST 27, TNMART 24 | | Bethune-Cookman @ Delaware State | ESPNU | DEST 24, BTHN 10 | | Kentucky @ South Carolina | ESPN | SC 38, KY 23 | | Friday, Oct. 5 |
| Matchup | TV | Time/Result | | Utah @ Louisville | ESPN | UT 44, LOU 35 | | Saturday, Oct. 6 |
| Matchup | TV | Time/Result | | Bowling Green @ Boston College | ESPNU | BC 55, BG 24 | | Central Michigan @ Ball State | | CMI 58, BALLST 38 | | Delaware @ New Hampshire | | NH 35, DE 30 | | Eastern Michigan @ Michigan | Big Ten Network | MI 33, EMI 22 | | Georgia Tech @ Maryland | Raycom/Lincoln Financial | MD 28, GATECH 26 | | Kansas @ Kansas State | FOX Sports Net | KS 30, KSST 24 | | Miami (Fla.) @ North Carolina | ESPN2 | NC 33, MIA 27 | | Minnesota @ Indiana | Big Ten Network | IN 40, MN 20 | | Northwestern @ Michigan State | Big Ten Network | NW 48, MIST 41 (OT) | | Richmond @ Towson | | TWST 23, RICH 21 | | Wisconsin @ Illinois | ESPN | IL 31, WI 26 | | Western Illinois @ Indiana State | | WIL 19, INST 7 | | West Virginia @ Syracuse | | WV 55, SYR 14 | | Dartmouth @ Yale | | YALE 50, DART 10 | | Holy Cross @ Brown | | HOLY 48, BRO 37 | | James Madison @ Northeastern | | JMAD 21, NEAST 14 | | Vanderbilt @ Auburn | Lincoln Financial | AUB 35, VANDY 7 | | Bucknell @ Colgate | | COLG 28, BUCK 24 | | Central Connecticut State @ St. Francis (PA.) | | CCTST 43, STFRPA 7 | | Cheyney @ Howard | | HOW 41, CHEY 14 | | Duquesne @ Marist | | DUQ 31, MARIST 21 | | Georgetown @ Pennsylvania | | PA 42, GTOWN 13 | | Harvard @ Cornell | | HARV 32, CORN 15 | | Iona @ La Salle | | IONA 56, LSLE 3 | | Jacksonville (Fl) @ Dayton | | DAY 49, JAX 3 | | Lehigh @ Fordham | | FORD 28, LEH 18 | | Monmouth (NJ) @ Sacred Heart | | MONNJ 49, SACHRT 8 | | Morehead State (KY) @ Davidson | | MOREHDST 49, DAVID 21 | | Northern Illinois @ Temple | | TEMP 16, NIL 15 | | Ohio @ Buffalo | | BUFF 31, OH 10 | | Wagner @ Robert Morris | | WAG 20, ROB 13 | | Wake Forest @ Duke | | WF 41, DUKE 36 | | Maine @ Hofstra | | HOF 38, ME 13 | | Savannah State @ Charleston Southern | | CHARSO 28, SAV 0 | | Butler @ Drake | | DRA 37, BUT 19 | | Coastal Carolina @ Furman | | FUR 27, CSTCAR 17 | | Louisiana Tech @ Mississippi | | MS 24, LATECH 0 | | North Greenville @ Presbyterian | | PRESBY 66, NGREEN 52 | | South Carolina State @ Norfolk State | | NRFST 20, SCST 13 (OT) | | San Diego @ Valparaiso | | SDG 41, VALPO 27 | | South Dakota State @ Georgia Southern | | GAS 41, SDST 38 | | TCU @ Wyoming | | WY 24, TCU 21 | | Wofford @ The Citadel | | WOFF 28, CIT 7 | | UC Davis @ North Dakota State | | NDST 35, DAVIS 16 | | Austin Peay @ Tennessee Tech | | AP 30, TNTECH 27 | | Eastern Kentucky @ Eastern Illinois | | EKY 28, EIL 21 | | Gardner-Webb @ Appalachian State | | APLST 45, GRDWB 7 | | UAB @ Mississippi State | | MSST 30, UAB 13 | | Houston @ Alabama | | AL 30, HOU 24 | | Illinois State @ Missouri State | | MOST 58, ILST 41 | | Miami (Ohio) @ Kent State | | MIAOH 20, KENTST 13 | | Mississippi Valley State @ Grambling | | GRAM 40, MSVALST 0 | | Northwestern State @ Nicholls State | | NICHST 58, NWST 0 | | Prairie View A&M @ Alcorn State | | PRARIE 17, ALCST 7 | | Sacramento State @ Weber State | | WBRST 26, SACST 7 | | Eastern Washington @ Montana | | MT 24, EWA 23 | | Georgia @ Tennessee |  CBS | TN 35, GA 14 | | Hampton @ Princeton | | HAMP 48, PRINCE 27 | | Iowa @ Penn State | ABC Regional | PSU 27, IA 7 | | North Carolina State @ Florida State | ABC Regional | FLST 27, NCST 10 | | Oklahoma @ Texas | ABC Regional | OK 28, TX 21 | | South Florida @ Florida Atlantic | ESPNU | SFL 35, FAU 23 | | Youngstown State @ Southern Illinois | CSTV | SIL 24, YST 17 | | Southern Utah @ Montana State | | MTST 7, SUT 3 | | Alabama State @ Jackson State | | JACKST 32, ALST 20 | | Arizona @ Oregon State | | ORST 31, AZ 16 | | Arizona State @ Washington State | FOX Sports Net | AZST 23, WAST 20 | | Idaho @ San Jose State | | SJST 28, ID 20 | | North Carolina A&T @ Morgan State | | MRGNST 22, NCAT 17 | | Stony Brook @ Albany | | ALBANY 24, STONYBRK 23 | | Fresno State @ Nevada | | FRE 49, NV 41 | | Northern Colorado @ Idaho State | | IDST 26, NCO 14 | | Northern Arizona @ Portland State | | NAZ 44, PORTST 43 | | Florida A&M @ Winston-Salem | | WS 27, FAMU 23 | | San Diego State @ Colorado State | | SDGST 24, COST 20 | | Columbia @ Lafayette | | LAF 29, CLMB 0 | | Elon @ Western Carolina | | ELON 38, WCAR 36 | | Virginia Tech @ Clemson | ESPN | VATECH 41, CLEM 23 | | William & Mary @ Villanova | | NOVA 63, WMMARY 24 | | Alabama A&M @ Southern | | ALAM 33, SO 28 | | Akron @ Western Michigan | | AKR 39, WMI 38 | | Arkansas State @ Louisiana-Monroe | | LAMON 30, ARST 13 | | Central Arkansas @ Sam Houston State | | CAR 35, SAMST 14 | | Colorado @ Baylor | | CO 43, BAY 23 | | Iowa State @ Texas Tech | | TXTECH 42, IAST 17 | | Liberty @ Toledo | | TOL 35, LIB 34 | | McNeese State @ Texas State-San Marcos | | MCN 41, SWTXST 20 | | North Texas @ La.-Lafayette | | LALAFAY 38, NTX 29 | | Stephen F. Austin @ Southeastern Louisiana | | SELOU 21, SFA 3 | | Stanford @ Southern California | Versus | STAN 24, USC 23 | | Tulane @ Army | ESPNU | ARMY 20, TLN 17 (OT) | | Chattanooga @ Arkansas | | AR 34, TNCHAT 15 | | Troy @ Florida International | | TROY 34, FIU 16 | | Virginia @ Middle Tennessee | CSS | VA 23, MITNST 21 | | Oklahoma State @ Texas A&M | FOX Sports Net | TXAM 24, OKST 23 | | UCF @ East Carolina | CSTV | ECA 52, UCF 38 | | Cincinnati @ Rutgers | ESPN2 | CIN 28, RUT 23 | | Florida @ LSU | CBS | LSU 28, FL 24 | | Notre Dame @ UCLA | ABC Regional | ND 20, UCLA 6 | | Ohio State @ Purdue | ABC Regional | OHST 23, PUR 7 | | UNLV @ Air Force | | AF 31, UNLV 14 | | Tulsa @ Texas-El Paso | | TXEP 48, TLS 47 | | Nebraska @ Missouri | ESPN | MO 41, NE 6 | | Sunday, Oct. 7 |
| Matchup | TV | Time/Result | | Utah State @ Hawaii | | HI 52, UTST 37 | | New Mexico State @ Boise State | ESPN | BST 58, NMST 0 |
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